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A multifactor regulatory circuit involving H-NS, VirF and an antisense RNA modulates transcription of the virulence gene icsA of Shigella flexneri

The icsA gene of Shigella encodes a structural protein involved in colonization of the intestinal mucosa by bacteria. This gene is expressed upon invasion of the host and is controlled by a complex regulatory circuit involving the nucleoid protein H-NS, the AraC-like transcriptional activator VirF,...

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Detalles Bibliográficos
Autores principales: Tran, Chi Nhan, Giangrossi, Mara, Prosseda, Gianni, Brandi, Anna, Di Martino, Maria Letizia, Colonna, Bianca, Falconi, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185424/
https://www.ncbi.nlm.nih.gov/pubmed/21724612
http://dx.doi.org/10.1093/nar/gkr521