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HIV-1 Integrase-DNA Recognition Mechanisms

Integration of a reverse transcribed DNA copy of the HIV viral genome into the host chromosome is essential for virus replication. This process is catalyzed by the virally encoded protein integrase. The catalytic activities, which involve DNA cutting and joining steps, have been recapitulated in vit...

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Detalles Bibliográficos
Autores principales: Kessl, Jacques J., McKee, Christopher J., Eidahl, Jocelyn O., Shkriabai, Nikolozi, Katz, Ari, Kvaratskhelia, Mamuka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185514/
https://www.ncbi.nlm.nih.gov/pubmed/21994566
http://dx.doi.org/10.3390/v1030713