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Maturation Pathways of Cross-Reactive HIV-1 Neutralizing Antibodies

Several human monoclonal antibodies (hmAbs) and antibody fragments, including the best characterized in terms of structure-function b12 and Fab X5, exhibit relatively potent and broad HIV-1 neutralizing activity. However, the elicitation of b12 or b12-like antibodies in vivo by vaccine immunogens ba...

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Detalles Bibliográficos
Autores principales: Xiao, Xiaodong, Chen, Weizao, Feng, Yang, Dimitrov, Dimiter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185542/
https://www.ncbi.nlm.nih.gov/pubmed/21994570
http://dx.doi.org/10.3390/v1030802