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Dual Role of p53 in Innate Antiviral Immunity

Tumor suppressor p53 is widely known as ‘the guardian of the genome’ due to its ability to prevent the emergence of transformed cells by the induction of cell cycle arrest and apoptosis. However, recent studies indicate that p53 is also a direct transcriptional target of type I interferons (IFNs) an...

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Detalles Bibliográficos
Autores principales: Rivas, Carmen, Aaronson, Stuart A., Munoz-Fontela, Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185551/
https://www.ncbi.nlm.nih.gov/pubmed/21994612
http://dx.doi.org/10.3390/v2010298