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Development of ST-246® for Treatment of Poxvirus Infections

ST-246 (Tecovirimat) is a small synthetic antiviral compound being developed to treat pathogenic orthopoxvirus infections of humans. The compound was discovered as part of a high throughput screen designed to identify inhibitors of vaccinia virus-induced cytopathic effects. The antiviral activity is...

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Detalles Bibliográficos
Autores principales: Jordan, Robert, Leeds, Janet M., Tyavanagimatt, Shanthakumar, Hruby, Dennis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185582/
https://www.ncbi.nlm.nih.gov/pubmed/21994624
http://dx.doi.org/10.3390/v2112409