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RNA Replicons - A New Approach for Influenza Virus Immunoprophylaxis

RNA replicons are derived from either positive- or negative-strand RNA viruses. They represent disabled virus vectors that are not only avirulent, but also unable to revert to virulence. Due to autonomous RNA replication, RNA replicons are able to drive high level, cytosolic expression of recombinan...

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Detalles Bibliográficos
Autor principal: Zimmer, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185613/
https://www.ncbi.nlm.nih.gov/pubmed/21994644
http://dx.doi.org/10.3390/v2020413