HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate

HIV-1 reverse transcriptase (RT) inhibitors currently used in antiretroviral therapy can be divided into two classes: (i) nucleoside analog RT inhibitors (NRTIs), which compete with natural nucleoside substrates and act as terminators of proviral DNA synthesis, and (ii) non-nucleoside RT inhibitors...

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Detalles Bibliográficos
Autores principales: Maga, Giovanni, Radi, Marco, Gerard, Marie-Aline, Botta, Maurizio, Ennifar, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185657/
https://www.ncbi.nlm.nih.gov/pubmed/21994659
http://dx.doi.org/10.3390/v2040880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185657/
https://www.ncbi.nlm.nih.gov/pubmed/21994659
http://dx.doi.org/10.3390/v2040880

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