Role of Gag in HIV Resistance to Protease Inhibitors

Cleavage of Gag and Gag-Pol precursors by the viral protease is an essential step in the replication cycle of HIV. Protease inhibitors, which compete with natural cleavage sites, strongly impair viral infectivity and have proven to be highly valuable in the treatment of HIV-infected subjects. Howeve...

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Detalles Bibliográficos
Autores principales: Clavel, François, Mammano, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185719/
https://www.ncbi.nlm.nih.gov/pubmed/21994687
http://dx.doi.org/10.3390/v2071411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185719/
https://www.ncbi.nlm.nih.gov/pubmed/21994687
http://dx.doi.org/10.3390/v2071411

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