Controversies in Targeted Therapy of Adult T Cell Leukemia/Lymphoma: ON Target or OFF Target Effects?

Adult T cell leukemia/lymphoma (ATL) represents an ideal model for targeted therapy because of intrinsic chemo-resistance of ATL cells and the presence of two well identified targets: the HTLV-I retrovirus and the viral oncoprotein Tax. The combination of zidovudine (AZT) and interferon-alpha (IFN)...

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Detalles Bibliográficos
Autores principales: Nasr, Rihab, Hajj, Hiba El, Kfoury, Youmna, de Thé, Hugues, Hermine, Olivier, Bazarbachi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185778/
https://www.ncbi.nlm.nih.gov/pubmed/21994752
http://dx.doi.org/10.3390/v3060750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185778/
https://www.ncbi.nlm.nih.gov/pubmed/21994752
http://dx.doi.org/10.3390/v3060750

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