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RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications

The RNA helicase family of RIG-I-like receptors (RLRs) is a key component of host defense mechanisms responsible for detecting viruses and triggering innate immune signaling cascades to control viral replication and dissemination. As cytoplasm-based sensors, RLRs recognize foreign RNA in the cell an...

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Detalles Bibliográficos
Autores principales: Ireton, Reneé C., Gale, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185779/
https://www.ncbi.nlm.nih.gov/pubmed/21994761
http://dx.doi.org/10.3390/v3060906