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A truncated form of CD9-partner 1 (CD9P-1), GS-168AT2, potently inhibits in vivo tumour-induced angiogenesis and tumour growth

BACKGROUND: Tetraspanins are transmembrane proteins known to contribute to angiogenesis. CD9 partner-1 (CD9P-1/EWI-F), a glycosylated type 1 transmembrane immunoglobulin, is a member of the tetraspanin web, but its role in angiogenesis remains to be elucidated. METHODS: We measured the expression of...

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Detalles Bibliográficos
Autores principales: Colin, S, Guilmain, W, Creoff, E, Schneider, C, Steverlynck, C, Bongaerts, M, Legrand, E, Vannier, J P, Muraine, M, Vasse, M, Al-Mahmood, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185932/
https://www.ncbi.nlm.nih.gov/pubmed/21863033
http://dx.doi.org/10.1038/bjc.2011.303