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Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain

Neuropathic pain is a debilitating clinical condition with few efficacious treatments, warranting development of novel therapeutics. We hypothesized that dysregulated translation regulation pathways may underlie neuropathic pain. Peripheral nerve injury induced reorganization of translation machiner...

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Detalles Bibliográficos
Autores principales: Melemedjian, Ohannes K, Asiedu, Marina N, Tillu, Dipti V, Sanoja, Raul, Yan, Jin, Lark, Arianna, Khoutorsky, Arkady, Johnson, Jessica, Peebles, Katherine A, Lepow, Talya, Sonenberg, Nahum, Dussor, Gregory, Price, Theodore J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186752/
https://www.ncbi.nlm.nih.gov/pubmed/21936900
http://dx.doi.org/10.1186/1744-8069-7-70