Functional Expression of Parasite Drug Targets and Their Human Orthologs in Yeast

BACKGROUND: The exacting nutritional requirements and complicated life cycles of parasites mean that they are not always amenable to high-throughput drug screening using automated procedures. Therefore, we have engineered the yeast Saccharomyces cerevisiae to act as a surrogate for expressing anti-p...

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Detalles Bibliográficos
Autores principales: Bilsland, Elizabeth, Pir, Pınar, Gutteridge, Alex, Johns, Alexander, King, Ross D., Oliver, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186757/
https://www.ncbi.nlm.nih.gov/pubmed/21991399
http://dx.doi.org/10.1371/journal.pntd.0001320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186757/
https://www.ncbi.nlm.nih.gov/pubmed/21991399
http://dx.doi.org/10.1371/journal.pntd.0001320

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