Cargando…

Nucleotide Discrimination with DNA Immobilized in the MspA Nanopore

Nanopore sequencing has the potential to become a fast and low-cost DNA sequencing platform. An ionic current passing through a small pore would directly map the sequence of single stranded DNA (ssDNA) driven through the constriction. The pore protein, MspA, derived from Mycobacterium smegmatis, has...

Descripción completa

Detalles Bibliográficos
Autores principales: Manrao, Elizabeth A., Derrington, Ian M., Pavlenok, Mikhail, Niederweis, Michael, Gundlach, Jens H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186796/
https://www.ncbi.nlm.nih.gov/pubmed/21991340
http://dx.doi.org/10.1371/journal.pone.0025723