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Nucleotide Discrimination with DNA Immobilized in the MspA Nanopore
Nanopore sequencing has the potential to become a fast and low-cost DNA sequencing platform. An ionic current passing through a small pore would directly map the sequence of single stranded DNA (ssDNA) driven through the constriction. The pore protein, MspA, derived from Mycobacterium smegmatis, has...
Autores principales: | Manrao, Elizabeth A., Derrington, Ian M., Pavlenok, Mikhail, Niederweis, Michael, Gundlach, Jens H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186796/ https://www.ncbi.nlm.nih.gov/pubmed/21991340 http://dx.doi.org/10.1371/journal.pone.0025723 |
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