CYLD regulates keratinocyte differentiation and skin cancer progression in humans

CYLD is a gene mutated in familial cylindromatosis and related diseases, leading to the development of skin appendages tumors. Although the deubiquitinase CYLD is a skin tumor suppressor, its role in skin physiology is unknown. Using skin organotypic cultures as experimental model to mimic human ski...

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Detalles Bibliográficos
Autores principales: Alameda, J P, Fernández-Aceñero, M J, Moreno-Maldonado, R, Navarro, M, Quintana, R, Page, A, Ramírez, A, Bravo, A, Casanova, M L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186900/
https://www.ncbi.nlm.nih.gov/pubmed/21900959
http://dx.doi.org/10.1038/cddis.2011.82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186900/
https://www.ncbi.nlm.nih.gov/pubmed/21900959
http://dx.doi.org/10.1038/cddis.2011.82

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