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Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania
The control of the protozoan parasite Leishmania relies on few drugs with unknown cellular targets and unclear mode of action. Several antileishmanials, however, were shown to induce apoptosis in Leishmania and this death mechanism was further studied in drug-sensitive and drug-resistant Leishmania...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186901/ https://www.ncbi.nlm.nih.gov/pubmed/21881603 http://dx.doi.org/10.1038/cddis.2011.83 |