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Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania

The control of the protozoan parasite Leishmania relies on few drugs with unknown cellular targets and unclear mode of action. Several antileishmanials, however, were shown to induce apoptosis in Leishmania and this death mechanism was further studied in drug-sensitive and drug-resistant Leishmania...

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Detalles Bibliográficos
Autores principales: Moreira, W, Leprohon, P, Ouellette, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186901/
https://www.ncbi.nlm.nih.gov/pubmed/21881603
http://dx.doi.org/10.1038/cddis.2011.83

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