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Roles of the Polycomb group proteins in stem cells and cancer

Polycomb group proteins have long been linked to the occurrence of different forms of cancer. Polycomb proteins form at least two distinct complexes, the Polycomb-repressive complexes 1 and 2 (PRC1 and PRC2). Some of the PRC complex subunits have been found to be overexpressed in a variety of differ...

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Detalles Bibliográficos
Autores principales: Richly, H, Aloia, L, Di Croce, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186902/
https://www.ncbi.nlm.nih.gov/pubmed/21881606
http://dx.doi.org/10.1038/cddis.2011.84