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Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies

Glycogen synthase kinase-3 (GSK-3) is ubiquitously expressed and unusually active in resting, non-stimulated cells. In mammals, at least three proteins (α, β1, and β2), generated from two different genes, gsk-3α and gsk-3β, are widely expressed at both the RNA and protein levels although some tissue...

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Detalles Bibliográficos
Autores principales: Medina, Miguel, Garrido, Juan Jose, Wandosell, Francisco G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186940/
https://www.ncbi.nlm.nih.gov/pubmed/22007157
http://dx.doi.org/10.3389/fnmol.2011.00024