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Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor
It has been assumed that premessenger ribonucleic acids (RNAs; pre-mRNAs) are spliced cotranscriptionally in the process of gene expression. However, in this paper, we report that splicing of Clk1/4 mRNAs is suspended in tissues and cultured cells and that intermediate forms retaining specific intro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187705/ https://www.ncbi.nlm.nih.gov/pubmed/21949414 http://dx.doi.org/10.1083/jcb.201107093 |