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EMILIN1–α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation
EMILIN1 promotes α4β1 integrin–dependent cell adhesion and migration and reduces pro–transforming growth factor–β processing. A knockout mouse model was used to unravel EMILIN1 functions in skin where the protein was abundantly expressed in the dermal stroma and where EMILIN1-positive fibrils reache...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187715/ https://www.ncbi.nlm.nih.gov/pubmed/21949412 http://dx.doi.org/10.1083/jcb.201008013 |