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Directed PCR-free engineering of highly repetitive DNA sequences

BACKGROUND: Highly repetitive nucleotide sequences are commonly found in nature e.g. in telomeres, microsatellite DNA, polyadenine (poly(A)) tails of eukaryotic messenger RNA as well as in several inherited human disorders linked to trinucleotide repeat expansions in the genome. Therefore, studying...

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Detalles Bibliográficos
Autores principales: Scior, Annika, Preissler, Steffen, Koch, Miriam, Deuerling, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187725/
https://www.ncbi.nlm.nih.gov/pubmed/21943395
http://dx.doi.org/10.1186/1472-6750-11-87