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LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes

BACKGROUND: It is known that retinoid receptor function is attenuated during T cell activation, a phenomenon that involves actin remodeling, suggesting that actin modification may play a role in such inhibition. Here we have investigated the role of actin dynamics and the effect of actin cytoskeleto...

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Detalles Bibliográficos
Autores principales: Ishaq, Mohammad, Lin, Bor-Ruei, Bosche, Marjorie, Zheng, Xin, Yang, Jun, Huang, Dawei, Lempicki, Richard A, Natarajan, Ven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187726/
https://www.ncbi.nlm.nih.gov/pubmed/21923909
http://dx.doi.org/10.1186/1471-2199-12-41