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Functional Evaluation of Genetic and Environmental Regulators of P450 mRNA Levels

Variations in the activities of Cytochrome P450s are one of the major factors responsible for inter-individual differences in drug clearance rates, which may cause serious toxicity or inefficacy of therapeutic drugs. Various mRNA level is one of the key factors for different activity of the major P4...

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Detalles Bibliográficos
Autores principales: Wang, Dazhi, Jiang, Zhengwen, Shen, Zhongyang, Wang, Hui, Wang, Beilan, Shou, Weihua, Zheng, Hong, Chu, Xun, Shi, Jinxiu, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187744/
https://www.ncbi.nlm.nih.gov/pubmed/21998633
http://dx.doi.org/10.1371/journal.pone.0024900