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Functional Evaluation of Genetic and Environmental Regulators of P450 mRNA Levels
Variations in the activities of Cytochrome P450s are one of the major factors responsible for inter-individual differences in drug clearance rates, which may cause serious toxicity or inefficacy of therapeutic drugs. Various mRNA level is one of the key factors for different activity of the major P4...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187744/ https://www.ncbi.nlm.nih.gov/pubmed/21998633 http://dx.doi.org/10.1371/journal.pone.0024900 |