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Spatial Segregation of BMP/Smad Signaling Affects Osteoblast Differentiation in C2C12 Cells

BACKGROUND: Bone morphogenetic proteins (BMPs) are involved in a plethora of cellular processes in embryonic development and adult tissue homeostasis. Signaling specificity is achieved by dynamic processes involving BMP receptor oligomerization and endocytosis. This allows for spatiotemporal control...

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Detalles Bibliográficos
Autores principales: Heining, Eva, Bhushan, Raghu, Paarmann, Pia, Henis, Yoav I., Knaus, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187766/
https://www.ncbi.nlm.nih.gov/pubmed/21998639
http://dx.doi.org/10.1371/journal.pone.0025163