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Dicer1 Depletion in Male Germ Cells Leads to Infertility Due to Cumulative Meiotic and Spermiogenic Defects

BACKGROUND: Spermatogenesis is a complex biological process that requires a highly specialized control of gene expression. In the past decade, small non-coding RNAs have emerged as critical regulators of gene expression both at the transcriptional and post-transcriptional level. DICER1, an RNAse III...

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Detalles Bibliográficos
Autores principales: Romero, Yannick, Meikar, Oliver, Papaioannou, Marilena D., Conne, Béatrice, Grey, Corinne, Weier, Manuela, Pralong, François, De Massy, Bernard, Kaessmann, Henrik, Vassalli, Jean-Dominique, Kotaja, Noora, Nef, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187767/
https://www.ncbi.nlm.nih.gov/pubmed/21998645
http://dx.doi.org/10.1371/journal.pone.0025241