3′UTR-Mediated Gene Silencing of the Mixed Lineage Leukemia (MLL) Gene

Translocations involving the Mixed Lineage Leukemia (MLL) gene generate in-frame fusions of MLL with more than 50 different partner genes (PGs). Common to all MLL translocations is the exchange not only of coding regions, but also of MLL and PG 3′-untranslated regions (3′UTRs). As a result, the MLL-...

Descripción completa

Detalles Bibliográficos
Autores principales: Gomez-Benito, Maria, Loayza-Puch, Fabricio, Oude Vrielink, Joachim, Odero, Maria D., Agami, Reuven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187771/
https://www.ncbi.nlm.nih.gov/pubmed/21998658
http://dx.doi.org/10.1371/journal.pone.0025449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187771/
https://www.ncbi.nlm.nih.gov/pubmed/21998658
http://dx.doi.org/10.1371/journal.pone.0025449

Ejemplares similares