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New Insight into the Molecular Mechanisms of the Biological Effects of DNA Minor Groove Binders

BACKGROUND: Bisbenzimides, or Hoechst 33258 (H258), and its derivative Hoechst 33342 (H342) are archetypal molecules for designing minor groove binders, and widely used as tools for staining DNA and analyzing side population cells. They are supravital DNA minor groove binders with AT selectivity. H3...

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Detalles Bibliográficos
Autores principales: Zhang, Xinbo, Zhang, Siyu Crystal, Sun, Dejun, Hu, Jiang, Wali, Anil, Pass, Harvey, Fernandez-Madrid, Felix, Harbut, Michael R., Tang, Naimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187808/
https://www.ncbi.nlm.nih.gov/pubmed/21998702
http://dx.doi.org/10.1371/journal.pone.0025822