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Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Injury by Inhibiting ROS-Activated ERK1/2 and p38MAPK Signaling Pathways in PC12 Cells

Hydrogen sulfide (H(2)S) has been proposed as a novel neuromodulator and neuroprotective agent. Cobalt chloride (CoCl(2)) is a well-known hypoxia mimetic agent. We have demonstrated that H(2)S protects against CoCl(2)-induced injuries in PC12 cells. However, whether the members of mitogen-activated...

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Detalles Bibliográficos
Autores principales: Lan, Aiping, Liao, Xinxue, Mo, Liqiu, Yang, Chuntao, Yang, Zhanli, Wang, Xiuyu, Hu, Fen, Chen, Peixi, Feng, Jianqiang, Zheng, Dongdan, Xiao, Liangcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187826/
https://www.ncbi.nlm.nih.gov/pubmed/21998720
http://dx.doi.org/10.1371/journal.pone.0025921