Chronic Effects of Palmitate Overload on Nutrient-Induced Insulin Secretion and Autocrine Signalling in Pancreatic MIN6 Beta Cells

BACKGROUND: Sustained exposure of pancreatic β cells to an increase in saturated fatty acids induces pleiotropic effects on β-cell function, including a reduction in stimulus-induced insulin secretion. The objective of this study was to investigate the effects of chronic over supply of palmitate upo...

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Detalles Bibliográficos
Autores principales: Watson, Maria L., Macrae, Katherine, Marley, Anna E., Hundal, Harinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187833/
https://www.ncbi.nlm.nih.gov/pubmed/21998735
http://dx.doi.org/10.1371/journal.pone.0025975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187833/
https://www.ncbi.nlm.nih.gov/pubmed/21998735
http://dx.doi.org/10.1371/journal.pone.0025975

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