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Accumulation of Wildtype and ALS-Linked Mutated VAPB Impairs Activity of the Proteasome

Cellular homeostasis relies on a tight control of protein synthesis, folding and degradation, in which the endoplasmic reticulum (ER) quality control and the ubiquitin proteasome system (UPS) have an instrumental function. ER stress and aberrant accumulation of misfolded proteins represent a patholo...

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Detalles Bibliográficos
Autores principales:	Moumen, Anice, Virard, Isabelle, Raoul, Cédric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187839/ https://www.ncbi.nlm.nih.gov/pubmed/21998752 http://dx.doi.org/10.1371/journal.pone.0026066

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