Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through up-regulation of FAK and Src

Advanced stages of epithelial carcinogenesis involve the loss of intercellular adhesion, but it remains unclear how proteins that regulate alterations in cell-cell and cell-matrix adhesion are deregulated to promote the early stages of cancer development. To address this, a three-dimensional human t...

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Detalles Bibliográficos
Autores principales: Alt-Holland, Addy, Sowalsky, Adam, Szwec-Levin, Yonit, Shamis, Yulia, Hatch, Harold, Feig, Larry A., Garlick, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188385/
https://www.ncbi.nlm.nih.gov/pubmed/21716326
http://dx.doi.org/10.1038/jid.2011.188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188385/
https://www.ncbi.nlm.nih.gov/pubmed/21716326
http://dx.doi.org/10.1038/jid.2011.188

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