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Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through up-regulation of FAK and Src
Advanced stages of epithelial carcinogenesis involve the loss of intercellular adhesion, but it remains unclear how proteins that regulate alterations in cell-cell and cell-matrix adhesion are deregulated to promote the early stages of cancer development. To address this, a three-dimensional human t...
Autores principales: | Alt-Holland, Addy, Sowalsky, Adam, Szwec-Levin, Yonit, Shamis, Yulia, Hatch, Harold, Feig, Larry A., Garlick, Jonathan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188385/ https://www.ncbi.nlm.nih.gov/pubmed/21716326 http://dx.doi.org/10.1038/jid.2011.188 |
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