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Hydrophobicity and Charge Shape Cellular Metabolite Concentrations

What governs the concentrations of metabolites within living cells? Beyond specific metabolic and enzymatic considerations, are there global trends that affect their values? We hypothesize that the physico-chemical properties of metabolites considerably affect their in-vivo concentrations. The recen...

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Detalles Bibliográficos
Autores principales: Bar-Even, Arren, Noor, Elad, Flamholz, Avi, Buescher, Joerg M., Milo, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188480/
https://www.ncbi.nlm.nih.gov/pubmed/21998563
http://dx.doi.org/10.1371/journal.pcbi.1002166