Using Structure to Explore the Sequence Alignment Space of Remote Homologs

Protein structure modeling by homology requires an accurate sequence alignment between the query protein and its structural template. However, sequence alignment methods based on dynamic programming (DP) are typically unable to generate accurate alignments for remote sequence homologs, thus limiting...

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Detalles Bibliográficos
Autores principales: Kuziemko, Andrew, Honig, Barry, Petrey, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188491/
https://www.ncbi.nlm.nih.gov/pubmed/21998567
http://dx.doi.org/10.1371/journal.pcbi.1002175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188491/
https://www.ncbi.nlm.nih.gov/pubmed/21998567
http://dx.doi.org/10.1371/journal.pcbi.1002175

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