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Using Structure to Explore the Sequence Alignment Space of Remote Homologs
Protein structure modeling by homology requires an accurate sequence alignment between the query protein and its structural template. However, sequence alignment methods based on dynamic programming (DP) are typically unable to generate accurate alignments for remote sequence homologs, thus limiting...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188491/ https://www.ncbi.nlm.nih.gov/pubmed/21998567 http://dx.doi.org/10.1371/journal.pcbi.1002175 |