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Formation of Regulatory Modules by Local Sequence Duplication
Turnover of regulatory sequence and function is an important part of molecular evolution. But what are the modes of sequence evolution leading to rapid formation and loss of regulatory sites? Here we show that a large fraction of neighboring transcription factor binding sites in the fly genome have...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188502/ https://www.ncbi.nlm.nih.gov/pubmed/21998564 http://dx.doi.org/10.1371/journal.pcbi.1002167 |