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Formation of Regulatory Modules by Local Sequence Duplication

Turnover of regulatory sequence and function is an important part of molecular evolution. But what are the modes of sequence evolution leading to rapid formation and loss of regulatory sites? Here we show that a large fraction of neighboring transcription factor binding sites in the fly genome have...

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Detalles Bibliográficos
Autores principales: Nourmohammad, Armita, Lässig, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188502/
https://www.ncbi.nlm.nih.gov/pubmed/21998564
http://dx.doi.org/10.1371/journal.pcbi.1002167