IRAK-2 Regulates IL-1-Mediated Pathogenic Th17 Cell Development in Helminthic Infection

Infection with the trematode parasite Schistosoma mansoni results in distinct heterogeneity of disease severity both in humans and in mice. In the experimental mouse model, severe disease is characterized by pronounced hepatic egg-induced granulomatous inflammation mediated by CD4 Th17 cells, wherea...

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Detalles Bibliográficos
Autores principales: Smith, Patrick M., Jacque, Berri, Conner, James R., Poltorak, Alexander, Stadecker, Miguel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188523/
https://www.ncbi.nlm.nih.gov/pubmed/21998578
http://dx.doi.org/10.1371/journal.ppat.1002272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188523/
https://www.ncbi.nlm.nih.gov/pubmed/21998578
http://dx.doi.org/10.1371/journal.ppat.1002272

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