Detecting autozygosity through runs of homozygosity: A comparison of three autozygosity detection algorithms

BACKGROUND: A central aim for studying runs of homozygosity (ROHs) in genome-wide SNP data is to detect the effects of autozygosity (stretches of the two homologous chromosomes within the same individual that are identical by descent) on phenotypes. However, it is unknown which current ROH detection...

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Detalles Bibliográficos
Autores principales: Howrigan, Daniel P, Simonson, Matthew A, Keller, Matthew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188534/
https://www.ncbi.nlm.nih.gov/pubmed/21943305
http://dx.doi.org/10.1186/1471-2164-12-460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188534/
https://www.ncbi.nlm.nih.gov/pubmed/21943305
http://dx.doi.org/10.1186/1471-2164-12-460

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