Activity Deprivation Induces Neuronal Cell Death: Mediation by Tissue-Type Plasminogen Activator

Spontaneous activity is an essential attribute of neuronal networks and plays a critical role in their development and maintenance. Upon blockade of activity with tetrodotoxin (TTX), neurons degenerate slowly and die in a manner resembling neurodegenerative diseases-induced neuronal cell death. The...

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Detalles Bibliográficos
Autores principales: Schonfeld-Dado, Eldi, Segal, Menahem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188552/
https://www.ncbi.nlm.nih.gov/pubmed/21998719
http://dx.doi.org/10.1371/journal.pone.0025919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188552/
https://www.ncbi.nlm.nih.gov/pubmed/21998719
http://dx.doi.org/10.1371/journal.pone.0025919

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