Influence of ROBO1 and RORA on Risk of Age-Related Macular Degeneration Reveals Genetically Distinct Phenotypes in Disease Pathophysiology

ROBO1 is a strong candidate gene for age-related macular degeneration (AMD) based upon its location under a linkage peak on chromosome 3p12, its expression pattern, and its purported function in a pathway that includes RORA, a gene previously associated with risk for neovascular AMD. Previously, we...

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Detalles Bibliográficos
Autores principales: Jun, Gyungah, Nicolaou, Michael, Morrison, Margaux A., Buros, Jacqueline, Morgan, Denise J., Radeke, Monte J., Yonekawa, Yoshihiro, Tsironi, Evangelia E., Kotoula, Maria G., Zacharaki, Fani, Mollema, Nissa, Yuan, Yang, Miller, Joan W., Haider, Neena B., Hageman, Gregory S., Kim, Ivana K., Schaumberg, Debra A., Farrer, Lindsay A., DeAngelis, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188561/
https://www.ncbi.nlm.nih.gov/pubmed/21998696
http://dx.doi.org/10.1371/journal.pone.0025775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188561/
https://www.ncbi.nlm.nih.gov/pubmed/21998696
http://dx.doi.org/10.1371/journal.pone.0025775

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