Peroral Amphotericin B Polymer Nanoparticles Lead to Comparable or Superior In Vivo Antifungal Activity to That of Intravenous Ambisome(®) or Fungizone™

BACKGROUND: Despite advances in the treatment, the morbidity and mortality rate associated with invasive aspergillosis remains unacceptably high (70–90%) in immunocompromised patients. Amphotericin B (AMB), a polyene antibiotic with broad spectrum antifungal activity appears to be a choice of treatm...

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Detalles Bibliográficos
Autores principales: Italia, Jagdishbhai L., Sharp, Andrew, Carter, Katharine C., Warn, Peter, Kumar, M. N. V. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188565/
https://www.ncbi.nlm.nih.gov/pubmed/21998690
http://dx.doi.org/10.1371/journal.pone.0025744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188565/
https://www.ncbi.nlm.nih.gov/pubmed/21998690
http://dx.doi.org/10.1371/journal.pone.0025744

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