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Fabrication Principles and Their Contribution to the Superior In Vivo Therapeutic Efficacy of Nano-Liposomes Remote Loaded with Glucocorticoids

We report here the design, development and performance of a novel formulation of liposome- encapsulated glucocorticoids (GCs). A highly efficient (>90%) and stable GC encapsulation was obtained based on a transmembrane calcium acetate gradient driving the active accumulation of an amphipathic wea...

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Detalles Bibliográficos
Autores principales: Avnir, Yuval, Turjeman, Keren, Tulchinsky, Deborah, Sigal, Alex, Kizelsztein, Pablo, Tzemach, Dina, Gabizon, Alberto, Barenholz, Yechezkel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188566/
https://www.ncbi.nlm.nih.gov/pubmed/21998684
http://dx.doi.org/10.1371/journal.pone.0025721