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Fabrication Principles and Their Contribution to the Superior In Vivo Therapeutic Efficacy of Nano-Liposomes Remote Loaded with Glucocorticoids
We report here the design, development and performance of a novel formulation of liposome- encapsulated glucocorticoids (GCs). A highly efficient (>90%) and stable GC encapsulation was obtained based on a transmembrane calcium acetate gradient driving the active accumulation of an amphipathic wea...
Autores principales: | Avnir, Yuval, Turjeman, Keren, Tulchinsky, Deborah, Sigal, Alex, Kizelsztein, Pablo, Tzemach, Dina, Gabizon, Alberto, Barenholz, Yechezkel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188566/ https://www.ncbi.nlm.nih.gov/pubmed/21998684 http://dx.doi.org/10.1371/journal.pone.0025721 |
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