Cargando…

The Energy Landscape Analysis of Cancer Mutations in Protein Kinases

The growing interest in quantifying the molecular basis of protein kinase activation and allosteric regulation by cancer mutations has fueled computational studies of allosteric signaling in protein kinases. In the present study, we combined computer simulations and the energy landscape analysis of...

Descripción completa

Detalles Bibliográficos
Autores principales: Dixit, Anshuman, Verkhivker, Gennady M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188581/
https://www.ncbi.nlm.nih.gov/pubmed/21998754
http://dx.doi.org/10.1371/journal.pone.0026071