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Age-Specific Incidence Data Indicate Four Mutations Are Required for Human Testicular Cancers
Normal human cells require a series of genetic alterations to undergo malignant transformation. Direct sequencing of human tumors has identified hundreds of mutations in tumors, but many of these are thought to be unnecessary and a result of, rather than a cause of, the tumor. The exact number of mu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188587/ https://www.ncbi.nlm.nih.gov/pubmed/21998737 http://dx.doi.org/10.1371/journal.pone.0025978 |