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Association of HLA-B*5801 allele and allopurinol-induced stevens johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis

BACKGROUND: Despite some studies suggesting a possible association between human leukocyte antigen, HLA-B*5801 and allopurinol induced Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN), the evidence of association and its magnitude remain inconclusive. This study aims to systematic...

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Detalles Bibliográficos
Autores principales: Somkrua, Ratchadaporn, Eickman, Elizabeth E, Saokaew, Surasak, Lohitnavy, Manupat, Chaiyakunapruk, Nathorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189112/
https://www.ncbi.nlm.nih.gov/pubmed/21906289
http://dx.doi.org/10.1186/1471-2350-12-118